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    Expanding the blood supply

    Blood transfusions are essential in surgery, trauma care, cancer treatment, and emergencies. But supply is often limited, especially when time is critical. 

    Type O blood is the most useful because it can be given to almost anyone. Avivo changes that. 

    We convert A, B, and AB blood types into Type O, dramatically increasing the amount of universal blood available without needing more donors. 

    Our approach is designed to work within existing systems, making it practical for hospitals, emergency responders, and military teams alike. 

    More usable blood. When and where it’s needed most. 

    Increasing transplants, reducing wait times

    Blood type is one of the biggest barriers in organ transplantation. It determines who can receive an organ and who must keep waiting. 

    As a result: 

    • Some patients wait longer, with worse outcomes.  
    • Some donated organs go unused because a match isn’t found in time.  

    Avivo removes this limitation. 

    By converting donor organs to a universal Type O, we enable them to be matched with any patient, regardless of blood type. 

    This means: 

    • More transplants  
    • Shorter wait times  
    • Fewer organs going to waste  

     

    Every donated organ has the potential to save a life. We help ensure it does. 

    What we do

    Blood type is determined by markers on the surface of cells. These markers control compatibility between donors and recipients. 

    Avivo uses enzymes to remove those markers. 

    This converts A, B, and AB blood types into Type O, the universal donor. 

    It’s a simple but powerful step that removes a major barrier in both transfusion and transplantation. 

    Blood group A

    A antigen

    Enzymes

    Blood group O

    H antigen

    How we’ll do it

    The enzymes will be integrated into standard blood processing and organ procurement workflows.

    Blood transfusions

    Enzymes can be added to blood bag systems at the point of whole blood or red blood cell collection.

    Organ transplants

    Enzymes can be added to preservation solutions used in organ perfusion devices.

    When you’ve been seeing someone for 10 years and they haven’t been transplanted because of blood type, it’s hard. You know they could be saved.

    Christopher Nguan, MD, FRCSC
    Kidney Transplant Urologist, Vancouver General Hospital
    Past Chief Medical Officer, Avivo

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    We're always looking to connect with those interested in joining us on our journey.

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